1. 毕业设计（论文）的内容和要求

1．文献查阅 掌握文献查阅的一般方法，学会使用计算机在中国期刊网、维普数据库、超星数字图书馆、美国化学学会（acs）数据库、英国皇家化学学会（rcs）数据库、elseiver、isi chemistry server、ei、ca 等检索资源上查阅关于oca合成的相关文献。

2．文献阅读及综述 阅读与课题相关的外文及中文文献，了解国内外的研究动态，撰写文献综述。

3．明确实验任务，拟定实验方案 根据所查阅文献的内容，确定实验内容及方案，拟定科学可行的研究计划。

2. 参考文献

[1] Wang HY, Wu WZ, Li ZJ, et al. 2,4-Dinitrobenzenesulfonic acid in an efficient Broslash;nsted acid-catalyzed controlled/living ring-opening polymerization of ε-caprolactone[J]. RSC Advance, 2014, 4: 55716-55722. [2] Liu JJ, Chen C, Li ZJ, et al. A squaramide and tertiary amine: an excellent hydrogen-bonding pair organocatalyst for living polymerization[J]. Polymer Chemistry, 2015, 6: 3754-3757. [3] Xu JX, Liu JJ, Li ZJ, et al. Three is company: dual intramolecular hydrogen-bond enabled carboxylic acid active in ring-opening polymerization. Polymer Chemistry, 2016, 7: 1111-1120. [4] Li XP, Zhang QG, Li ZJ, et al. Tripodal hydrogen bond donor binding with sulfonic acid enables ring-opening polymerization. Polymer Chemistry, 2016, 7: 1368-1374. [5] Xia HD, Kan SL, Li ZJ, et al. N-Heterocyclic Carbenes as Organocatalysts in controlled/living ring-Opening Polymerization of O-Carboxyanhydrides Derived from L-Lactic Acid and L-Mandelic Acid[J]. Journal of Polymer Science, Part A: Polymer Chemistry, 2014, 52: 2306-2315. [6] Trollsaring;s M, Hawker CJ, Hedrick JL, et al. A Mild and Versatile Synthesis for the Preparation of Thiol-Functionalized Polymers[J]. Macromolecules, 1998, 31: 5960-5963. [7] Carrot G, Hilborn JG, Trollsaring;s M, et al. Two General Methods for the Synthesis of Thiol-Functional Polycaprolactones[J]. Macromolecules, 1999, 32: 5264-5269. [8] Carrot G., Hilborn J, Hedrick JL, et al. Novel Initiators for Atom Transfer Radical and Ring-Opening Polymerization: A New General Method for the Preparation of Thiol-Functional Polymers[J]. Macromolecules, 1999, 32: 5171-5173. [9] Kalarickal NC, Rimmer S, Sarker P, et al. Thiol-Functionalized Poly(ethylene glycol)-b-polyesters: Synthesis and Characterization[J]. Macromolecules, 2007, 40: 1874-1880. [10] Hedfors C, Ostmark E, Malmstrouml;m E, et al. Thiol End-Functionalization of Poly(ε-caprolactone), Catalyzed by Candida antarctica Lipase B[J]. Macromolecules, 2005, 38: 647-649. [11] 许 宁, 王 睿等. 端基为巯基的聚己内酯的合成[J]. 高等学校化学学报, 2007, 28(9): 1791-1795. [12]Vert M. Aliphatic polyesters: great degradable polymers that cannot do everything[J]. Biomacromolecules, 2005,6(2): 538-546. [13]Kricheldorf HR. Syntheses and application of polylactides[J]. Chemosphere, 2001,43(1):49-54. [14]Jianjun Cheng, Qian Yin, et al. Drug-Initiated Ring-Opening Polymerization of O-Carboxyanhydrides for the Preparation of Anticancer Drug#8722;Poly (O-carboxyanhydride) Nanoconjugates[J]. Biomacromolecules, 2013. [15]Steinb#252;chel A, Valentin HE. Diversity of bacterial polyhydroxyalkanoic acids[J]. FEMS Microbiology Letters, 1995,128(3): 219-228. [16]Carothers WH. Polymers and polyfunctionality[J]. Transactions of the Faraday Society, 1936,32: 39-49. [17]Kajiyama T, Kobayashi H, Taguchi T, et al. Improved synthesis with high yield and increased molecular weight of poly (α,β-malic acid) by direct polycondensation[J]. Biomacromolecules, 2004,5(1): 169-174. [18]Simmons TL, Baker GL. Poly (phenyllactide): Synthesis, characterization, and hydrolytic degradation[J]. Biomacromolecules, 2001,2(3): 658-663.

3. 毕业设计（论文）进程安排

2017.12.25~2017.12.12 确定课题，下达任务书，查阅文献，做好开题前期工作 2018.1.12~2018.3.19 查阅文献，做出研究方案，完成外文翻译和开题报告，开始实验 2018.3.20~2018.3.24 总结前一阶段工作，完成中期自检和中期汇报，确定下一阶段目标 2018.3.25~2018.4.30 扩展课题研究范围，改进实验方案，对 数据整理分析，撰写论文 2018.5.1~2018.6.7 完善毕业论文 2018.6.7~2018.6.14 准备毕业答辩