全文总字数：2869字

1. 1. 毕业设计（论文）的内容、要求、设计方案、规划等

1 前言：与本课题有关的国内外最新研究进展，立题意义。

2 方案拟定：科学合理，具有可行性。论文时间安排：

（1）2017.2.27―2017.3.5：阅读文献。熟悉掌握以下概念，基本操作流程，和研究意义：解淀粉芽孢杆菌，突变体库，difficidin。

2. 参考文献（不低于12篇）

[1] fan b, li y-l, li l, et al. malonylome analysis of rhizobacterium bacillus amyloliquefaciens fzb42 reveals involvement of lysine malonylation in polyketide synthesis and plant-bacteria interactions [j]. journal of proteomics, 2016, (154):1-12.

[2] chen x h, scholz r, borriss m, et al. difficidin and bacilysin produced by plant-associated bacillus amyloliquefaciens are efficient in controlling fire blight disease [j]. j biotechnol, 2009, 140(1-2):38-44.

[3] wu l, wu h, chen l, et al. difficidin and bacilysin from bacillus amyloliquefaciens fzb42 have antibacterial activity against xanthomonas oryzae rice pathogens [j]. sci rep, 2015, 5:12975.