1. 毕业设计（论文）的内容和要求

目前在我国急性紧急梗死的发病率逐年上升，且死亡率居高不下。

值得一提的是，心肌梗死发病前期会有较为明显的先兆症状，但是很多病患容易忽视这些症状。

心肌钙蛋白是心肌损伤坏死的标志物，对急性心肌梗死的诊断和危险分层有着极其重要的临床意义，对其进行早期监测以及快速原位检测是目前的研究中亟待解决的问题。

2. 参考文献

[1] Wang Z, Huang B, Ying D, et al. Highly Photocatalytic ZnO/In2O3 Heteronanostructures Synthesized by a Coprecipitation Method[J]. Journal of Physical Chemistry C, 2014, 113(11):4612-4617. [2] Harvey S P, Mason T O, Gassenbauer Y, et al. Surface versus bulk electronic/defect structures of transparent conducting oxides: I. Indium oxide and ITO[J]. Journal of Physics D, 2015, 39(39):3959. [3] Cao S W, Liu X F, Yuan Y P, et al. Solar-to-fuels conversion over In 2 O 3 /g-C 3 N 4 hybrid photocatalysts[J]. Applied Catalysis B Environmental, 2014, 147:940-946. [4] Yin W, Jing S, Cao M, et al. In(OH)3 and In2O3 Micro/Nanostructures: Controllable NaOAc-Assisted Microemulsion Synthesis and Raman Properties[J]. Journal of Physical Chemistry C, 2014, 113(45):19493-19499. [5] Sun X, Hao H, Ji H, et al. Nanocasting synthesis of In2O3 with appropriate mesostructured ordering and enhanced gas-sensing property.[J]. Acs Applied Materials Interfaces, 2014, 6(1):401-9. [6] A. Vomiero, M. Ferroni, E. Comini, et al. Preparation of Radial and Longitudinal Nanosized Heterostructures of In2O3 and SnO2[J]. Nano Letters, 2016, 7(12):3553-3558. [7] Zang W, Nie Y, Dan Z, et al. Core#8211;Shell In2O3/ZnO Nanoarray Nanogenerator as a Self-Powered Active Gas Sensor with High H2S Sensitivity and Selectivity at Room Temperature[J]. Journal of Physical Chemistry C, 2014, 118(17):9209#8211;9216. [8] Debeila M A, Wells R P K, Anderson J A. Influence of water and pretreatment conditions on CO oxidation over Au/TiO2#8211;In2O3 catalysts[J]. Journal of Catalysis, 2016, 239(1):162-172. [9] Ao L, Guo X L, Hui H Z, et al. Fully Solution-Processed Low-Voltage Aqueous In2O3 Thin-Film Transistors Using an Ultrathin ZrOx Dielectric[J]. Acs Appl Mater Interfaces, 2014, 6(20):17364-17369. [10] Kim K, Park C, Kwon D, et al. Silicon nanowire biosensors for detection of cardiac troponin I (cTnI) with high sensitivity[J]. Biosensors Bioelectronics, 2016, 77:695-701. [11] Zuo J, Zhao X, Ju X, et al. A New Molecularly Imprinted Polymer (MIP)‐based Electrochemical Sensor for Monitoring Cardiac Troponin I (cTnI) in the Serum[J]. Electroanalysis, 2016, 28(9):2044-2049. [12] Fathil M F M, Arshad M K M, Ruslinda A R, et al. Substrate-Gate Coupling in ZnO-FET Biosensor for Cardiac Troponin I Detection[J]. Sensors Actuators B Chemical, 2016, 242:1142-1154. [13] Xiao X, Kuang Z, Slocik J M, et al. Advancing Peptide-Based Biorecognition Elements for Biosensors Using In-Silico Evolution.[J]. Acs Sensors, 2018, 3(5):1024. [14] Sarangadharan I, Wang S L, Sukesan R, et al. Single drop Whole Blood Diagnostics: Portable Biomedical Sensor for cardiac Troponin I detection[J]. Analytical Chemistry, 2018, 90(4):acs.analchem.7b05018. [15] Liu Q, Aroonyadet N, Song Y, et al. Highly Sensitive and Quick Detection of Acute Myocardial Infarction Biomarkers Using In2O3 Nanoribbon Biosensors Fabricated Using Shadow Masks[J]. Acs Nano, 2016, 10(11):10117-10125. [16] Zhou W, Li K, Wei Y, et al. Ultrasensitive label-free optical microfiber coupler biosensor for detection of cardiac troponin I based on interference turning point effect.[J]. Biosensors Bioelectronics, 2018, 106:99-104.

3. 毕业设计（论文）进程安排

2019.01.11-2019.02.20 文献调研，开题报告,拟定实验方案； 2019.02.20-2019.05.10 开展实验工作，完成数据收集； 2019.05.10-2019.06.10 数据整理，撰写论文，准备答辩。