1. 毕业设计（论文）的内容和要求

在软骨修复过程中，前期研究发现单层支架材料对于软骨损伤的修复效果十分有限。

基于此近年来发展了依据软骨多层结构而构建具有多层结构的软骨修复体，这种软骨修复体的基本结构是上层模拟关节软骨的结构，如软骨结构中的浅表层、过渡层，这种支架的下层主要模拟软骨靠近软骨下骨结构，如软骨中的钙化层、放射层，上述骨/软骨支架旨在模拟软骨不同层区的生理和力学环境，使得这种一体化支架满足关节软骨各层区修复的要求，使得关节软骨各层区之间有连续的过渡，采用这种方式修复病变的关节软骨能够取得更为优异的修复效果。

2. 参考文献

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3. 毕业设计（论文）进程安排

1. 2017.12-2018.1 文献调研及路线设计； 2. 2018.2-2018.6 实验合成及工艺路线优化； 3. 2018.6 数据整理及论文写作。