1. 毕业设计（论文）的内容和要求

1）查阅酶法合成酯的文献资料； 2）制订详细的实验研究方案，撰写开题报告； 3）开展酶法合成呋喃二甲酸二异戊酯的工艺实验研究； 4）整理分析实验研究数据结果，完成毕业论文；

2. 参考文献

[1]Zhou lin, Cai miaoyan, Guo siyuan et al.Progress in the Application of Macroporous Adsorption Resin[J].Journal of Kunming University of Science and Technology ( Science and Technology), 200, 28(6): 99-102. [2]Klibanov A M. ChemInform Abstract: Improving Enzymes by Using them in Organic Solvents[J]. Cheminform, 2001, 32(14):no-no. [3]Fankhausernoti A, Grob K. Migration of plasticizers from PVC gaskets of lids for glass jars into oily foods: Amount of gasket material in food contact, proportion of plasticizer migrating into food and compliance testing by simulation[J]. Trends in Food Science Technology, 2006, 17(3):105-112. [4]肖禄生. 脂肪酶催化酯合成的研究[D]. 上海化工研究院，2003. [5]Dyck S M O V, Lemi#232;re G L F, Jonckers T H M, et al. Kinetic resolution of a dihydrobenzofuran-type neolignan by lipase-catalysed acetylation[J]. Tetrahedron Asymmetry, 2001, 12(5):785-789. [6]Jr G L, Ostby J, Furr J, et al. Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat.[J]. Toxicological Sciences, 2000, 58(2):350-365. [7]王琦，贾润礼. 聚氯乙烯增塑剂的研究[J]. 绝缘材料，2007，40(5):38-41. [8]陆杰，代园园，罗慧，等. 邻苯二甲酸二异壬酯致小鼠肝组织氧化损伤的研究[J]. 中国环境科学，2015，35(1):285-290. [9]Fankhausernoti A, Grob K. Migration of plasticizers from PVC gaskets of lids for glass jars into oily foods: Amount of gasket material in food contact, proportion of plasticizer migrating into food and compliance testing by simulation[J]. Trends in Food Science Technology, 2006, 17(3):105-112. [10]司俊杰. 我国增塑剂行业发展现状及绿色增塑剂的未来[J]. 增塑剂，2011(2):3-8. [11]周洁，闫建强，蒋伟. 一种PVC聚酯增塑剂及其制备方法和应用:CN 104945783 B[P]. 2016. [12]肖禄生. 脂肪酶催化酯合成的研究[D]. 上海化工研究院，2003. [13]Wang W G, Qiang W U, Bao-Kun H U, et al. Comparative Study on Determination Methods of Residual Protained in Grifolan[J]. Edible Fungi of China, 2003. [14]张玉霞，赵继华，杜中玉，等. AOT/Triton X-100混合反胶束体系中假丝酵母脂肪酶催化蓖麻油水解的活性[J]. 物理化学学报，2007，23(9):1483-1486. [15]郭明，许禄. 有机化合物的疏水性参数的计算──结构片断常数法[J]. 新疆大学学报(自然科学版)，1997，14(1):65-71. [16]刘幽燕，许建和，刘洪来，等. 反应条件对脂肪酶酯化活性和对映选择性的影响[J]. 高校化学工程学报，1999(4):372-376.

3. 毕业设计（论文）进程安排

2018.1.1-2018.2.28 文献查阅和撰写开题报告 2018.3.1-2018.5.31 实验研究 2018.6.1-2018.6.10 数据整理和论文写作 2018.6.10-2018.6.15 论文修改和完成答辩