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起讫日期

设计（论文）各阶段工作内容

备 注

2015.12-2016.1

文献查阅，完成开题报告，熟悉实验仪器。

2016.2-20163

.以5-氮胞嘧啶和2-脱氧尿苷为底物用N-脱氧核糖转移酶催化合成地西他滨，并进行鉴定。

2016.3-2016.4

考察反应pH、温度对地西他滨转化率的影响。

2016.4-2016.5

考察底物浓度、底物摩尔比对地西他滨转化率的影响。

2016.5-2016.6

考察酶添加量对地西他滨转化率的影响。