含荧光基团蒽的水溶性分子探针的合成及性质研究任务书
2020-05-24 12:33:02
1. 毕业设计(论文)的内容和要求
荧光探针是超分子科学中最为引人入胜的领域之一,它的基本设计思路是在荧光染料母体(荧光团)上引入受体单元(识别基团),金属离子与受体单元相结合或发生化学反应,并最终影响荧光团的光物理性质,通过荧光的变化如荧光强度的变化、荧光光谱的移动、荧光寿命的变化尤其是荧光强度的变化,直观地体现金属离子的存在。
它的主要功能包括分子识别和将识别信息转换成荧光信号两部分。
识别是超分子化学的核心内容,是分子存贮和超分子读取分子信息的过程。
2. 参考文献
[1] Zhang, G Q.; Yang, G Q.; Wang, S. Q. et al. A Highly Fluorescent Anthracene-Containing Hybrid Material Exhibiting Tunable Blue-Green Emission Based on the Formation of an Unusual "T-Shaped" Excimer, Chem. Eur. J. 2007, 13, 3630-3635. [2] Wang, C.; Abboud, K.A.;Phanstiel IV,O. Synthesis and Characterization of N1- (4-Toluenesulfonyl)-N1- (9-anthracenemethyl) triamines, J.Org. Chem., 2002,67(22): 7865-7868. [3] Morozumi, T.; Anada, T.; Nakamura, H. New Fluorescent "Off-On" Behavior of 9-Anthryl Aromatic Amides through Controlling the Twisted Intramolecular Charge Transfer Relaxation Process by Complexation with Metal Ions, J. Phys. Chem. B.,2001, l05(15): 2923-2931. [4] Badugu, R.; Lakowicz, J. R.; Geddes, C. D., Cyanide-sensitive fluorescent probes,Dyes Pigments, 2005, 64, 49-55. [5] Chen, Q. Y.;Chen, C. F. A new fluorescent as well as chromogenic chemosensor for anions based on an anthracene carbamate derivative, Tetrahedron Lett., 2004, 45,6493-6496 [6] 李立冬,吴玉芹,秦大斌.9,10-二( 苯亚甲基-硫亚甲基) 蒽的合成及其对 Cu2 的识别[J].化学研究与应用,2006,18( 1) : 60 - 63. [7] Ghosh K,Saha I. Selective sensing of Zn( Ⅱ) ion by asimple anthracene - based tripodal chemosensor[J].Tet-rahedron Letters,2010,51: 4995-4999. [8] 夏之宁.光分析化学[M].重庆:重庆大学出版社,2004. [9] 李娜,刘美玲,尹文婷等.罗丹明基 ”OFF-ON” 型荧光探针研究的一些新进展. 有机化学, 2011, 31(1): 39-53 [10]吴世康.超分子光化学导论:基础与应用.北京:科学出版社,2005 [11]许金钩,王尊本.荧光分析法.北京:科学出版社, 2006 [12] 艾小红,杨世柱.新型带荧光基团葱的Resorcinarens的合成[J].华南师范大学学报(自然科学版),1999(3):49. [13] 葛凤燕,闰喜龙,潘惠英等含活性基荧光素衍生物化学通报,2005,3:167-171 [14] Hennrich, G.; Walther, W.; Resch-Genger, U. et al. Cu(II)一and Hg(II)-Induced Modulation of the Fluorescence Behavior of a Redox-Active Sensor Molecule, Inorg. Chem., 2001, 40, 641-644. [15] Marquis, D.; Desvergne, J.-P.; Bouas-Laurent, H.Photoresponsive Supramolecular Systems: Synthesis and Photophysical Study of Bis-(9,10-anthracenediyl)coronands AAOnOn, J. Org. Chem, 1995, 60(24):7984-7996
3. 毕业设计(论文)进程安排
见附件。