1. 毕业设计（论文）的内容和要求

以对苯二甲醚为起始原料，在bf3(c2h5)2 催化下，与多聚甲醛反应合成二甲氧基柱[5]芳烃；用bbr3将甲氧基还原为羟基，全羟基柱[5]芳烃在氮气保护条件下与氯乙酸乙酯反应，生产全乙酸乙酯基取代的柱[5]芳烃；用弄naoh溶液将酯基水解，即可得到最终产物。

2. 参考文献

[1] ogoshi, t., kanai, s., fujinami, s., et al. para-bridged symmetrical pillar[5]arenes, their lewis acid catalyzed synthesis and host-guest property [j]. j. am. chem. soc., 2008, 130(15), 5022~5023.

[2].ogoshi, t., hashizume, m., yamagishi, t., nakamoto, y., synthesis, conformational and host-guest properties of water-soluble pillar[5]arene[j]. chem. commun., 2010,46(21), 37083710.

[3].ma,y., ji, x., xiang, f., et al. a cationic water-soluble pillar[5]arene, synthesis and host guest complexation with sodium 1-octanesulfonate[j] .chem. commun., 2011 47(45), 1234012342.

3. 毕业设计（论文）进程安排