1. 毕业设计（论文）的内容和要求

1.文献查阅

从查阅文献着手，在中国期刊网，维普数据库，超星数字图书馆，美国化学学会(acs)数据库，ca，sci等检索资源上查阅有关双齿催化剂合成的相关文献。

2. 参考文献

[1] shibahara, f.; yoshida, a.; murai, t., copper-catalyzed oxidative desulfurization-promoted intramolecular cyclization of thioamides using molecular oxygen as an oxidant : an efficient route to five- to seven-membered nitrogen-containing heterocycles. cheminform 2008, 37 (6), 646-647.

[2] de, t. p.; boverie, s.; becker, b.; antoine, m. h.; nguyen, q. a.; francotte, p.; counerotte, s.; sebille, s.; pirotte, b.; lebrun, p., 3-alkylamino-4h-1,2,4-benzothiadiazine 1,1-dioxides as atp-sensitive potassium channel openers: effect of 6,7-disubstitution on potency and tissue selectivity. journal of medicinal chemistry 2005, 48 (15), 4990-5000.

[3] glycosidation via oxidative activation of a thioether, see review: k. c. nicolaou, h. j. mitchell, angew. chem., int. ed. 2001, 40, 1576.

3. 毕业设计（论文）进程安排

2016.12.14-2016.12.23熟悉反应原理和实验操作，查阅文献，确定课题，撰写任务书

2016.12.24-2017.01.13确定实验方案，对课题进行初步实验，完成开题报告

2017.01.14-2017.06.02对前一阶段研究内容进行中期汇报，完成中期自检，确定下一步实验方案